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±¸°­ ³» Helicobacter pylori

Helicobacter pylori in the Oral Cavity

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Abstract

À§¿° ¹× À§¾Ï µîÀÇ ¹ß»ý°ú °ü·ÃµÇ¾î ÀÖ´Â Helicobacter pylori(H. pylori)´Â ±¸°­ÀÇ Ä¡ÅÂ¿Í Å¸¾×¿¡¼­ ÁÖ·Î ¹ß°ßÀÌ µÈ´Ù. À¯³â½ÃÀý µ¿¾È ÁÖ·Î °¨¿°µÇ´Â °ÍÀ¸·Î ¾Ë·ÁÁ® ÀÖÁö¸¸ °¨¿°°æ·Î´Â ºÒºÐ¸íÇÏ´Ù. ±¸°­ÀÌ H. pyloriÀÇ µÎ ¹ø° ¼­½ÄÁö·Î¼­ Àü¿°°æ·Î ¹× À§Àå³» H. pyloriÀÇ Á¦±Õ ÈÄ Àç°¨¿°¿¡ Áß¿äÇÑ ¿µÇâÀ» ³¢Ä¥ ¼ö ÀÖ´ÂÁö´Â ³íÀïÀÌ µÇ°í ÀÖ´Ù. µû¶ó¼­ º» ÀúÀÚ´Â ¹®Çå°íÂûÀ» ÅëÇÏ¿© ±¸°­ ³»¿¡ Á¸ÀçÇÏ´Â H. pylori¿¡ °üÇÏ¿© ¾Ë¾Æº¸°íÀÚ ÇÏ¿´´Ù. À§Àå¿¡ Á¸ÀçÇÏ´Â H. pylori´Â À§Àειݻ糪 ±¸Åä¿¡ ÀÇÇØ ±¸°­ ³» ¹ßÇöµÉ ¼öµµ ÀÖÀ¸³ª, ±¸°­°ú À§ÀÇ °¨¿°Àº ¼­·Î °ü·Ã¼ºÀÌ ¾ø´Â °ÍÀ¸·Î º¸°íµÇ°í ÀÖ´Ù. Áø´Ü¹æ¹ýÀ¸·Î´Â Ç÷ûÇÐÀû°Ë»ç, ¿ä¼ÒÈ£±â°Ë»ç, ÁßÇÕÈ¿¼Ò¿¬¼â¹ÝÀÀ(polymerase chain reaction: PCR)¹æ¹ý, Urease°Ë»ç, Á¶Á÷°Ë»ç µîÀÌ ÀÖÀ¸³ª, Ÿ¾×°ú Ä¡Å¿¡¼­´Â nested PCR ¹æ¹ýÀÌ ÁÖ·Î ÃßõµÇ¾î Áø´Ù. ±¸°­ ³» °¨¿°À²Àº ´Ù¾çÇÏ°Ô ³ªÅ¸³ª¸ç, Ä¡°úÁúȯ°úÀÇ ¿¬°ü¼ºÀº ¾ø´Â °ÍÀ¸·Î »ç·áµÈ´Ù. ±×·¯³ª Ä¡ÁÖÁúȯ ȯÀÚÀÇ ±¸°­ ³»¿¡¼­ ¹ßÇöÀ²Àº ³ô°Ô ³ªÅ¸³ª¹Ç·Î, ÁÖÀÇ°¡ ¿ä±¸µÇ¸ç Çâ±Õ ±¸°­¼¼Ã´Á¦ÀÇ »ç¿ëÀÌ ±ÇÀ¯µÈ´Ù. °á°úÀûÀ¸·Î ±¸°­ ³» H. pylori´Â Á¤»ó¼¼±ÕÃÑÀ¸·Î »ç·áµÇ¸ç, ÇâÈÄ ±¸°­³» H. pylori¿¡ °üÇÑ Ãß°¡ÀûÀÎ ¸¹Àº ¿¬±¸°¡ ÇÊ¿äÇϸ®¶ó »ç·áµÈ´Ù.

Helicobacter pylori(H. pylori) associated with gastritis and gastric cancer is mainly detected dental plaque and saliva in the oral cavity. Most infection is probably acquired in childhood, but the route of transmission is not clear. The oral cavity has been indicated as secondary reservoir of H. pylori, and may therefore be argued in the route of transmission and reinfection of the stomach which follows treatment of H. pylori infection. So this review aimed to discuss about H. pylori in the oral cavity. H. pylori in stomach can appear in the oral cavity by gastroesophageal reflex or vomiting, but infection of stomach and oral cavity is different. Diagnostic methods are serological method, urea breath test, PCR method, urease test, histologic method and so on. Nested PCR recommend for detection of H. pylori in saliva and dental plaque. H. pylori infection in the oral cavity appear variously and is no relation with dental diseases. The antimicrobial mouthrinse recommend in patients with periodontal diseases because of high detection rate fo H. pylori. Thus H. pylori may be considered as the normal oral microflora.

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dental diseases; diagnostic method; Helicobacter pylori; normal oral microflora; oral cavity

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